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Chlorothiazide should be used cautiously in patients with renal disease resulting in severe renal impairment because the drug decreases the glomerular. Easy to read FDA package insert, drug facts, dosage and administration, and adverse effects for Diuril (Chlorothiazide). Chlorothiazide sodium for injection, USP is a diuretic and a vial containing: Chlorothiazide sodium equiva- . toxicity. Refer to the package insert for lithium.

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Minor Diuretics can increase urinary frequency, which may aggravate bladder symptoms.

Moderate Patients receiving a diuretic during treatment with fluoxetine may be iduril greater risk of developing syndrome of inappropriate antidiuretic hormone secretion SIADH.

Major Pimozide is associated with a well-established risk of QT prolongation and torsade de pointes TdP.

Adjustments to diuretic therapy may be needed in some patients. Patients should be informed about measures to prevent orthostatic hypotension, such as sitting on the edge of the bed for several minutes prior to standing in the morning, or rising slowly from a seated position.

Moderate Topiramate is a carbonic anhydrase inhibitor. Belladonna Alkaloids; Ergotamine; Phenobarbital: Moderate There is potential for additive hypotensive effects when conivaptan is coadministered with antihypertensive agents. According to the manufacturer, chlorothiazide is specifically contraindicated in patients with sulfonamide hypersensitivity. Moderate Patients receiving a diuretic during treatment with vortioxetine may be at greater risk of developing syndrome of inappropriate antidiuretic hormone secretion SIADH.

High doses of some thiazide diuretics have been used off-label to suppress lactation, and thus should be used with caution during the establishment of breast-feeding.


Moderate Thiazides may increase blood levels and therefore potentiate the actions of amphetamines. Major Avoid concomitant use of arsenic trioxide with thiazide diuretics.

Moderate Use caution when prescribing sulfate salt bowel preparation in patients taking concomitant medications that may affect renal function such as diuretics. Directions for Reconstitution Use aseptic technique. Discontinuation of escitalopram should be considered in patients who develop symptomatic hyponatremia. Moderate Fish diuri, supplements may cause mild, dose-dependent reductions in systolic or diastolic blood pressure in untreated hypertensive patients.

Information on oral dosing in this age group is supported by evidence from empiric use in pediatric patients and published literature regarding the treatment of hypertension in such patients.

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Disclaimer The authors make no claims of the accuracy of the information contained herein; and these suggested doses are not a substitute for clinical judgment. Discontinuation of paroxetine should be considered in patients who develop symptomatic hyponatremia. Salicylates inhibit renal prostaglandin synthesis, which can lead to fluid retention and increased peripheral vascular resistance. In diabetic patients dosage adjustments of insulin or oral hypoglycemic agents may be required.

If possible, patients duuril not take their antihypertensive medication 24 hours before receiving amifostine. In cases of diuretic resistance, to 1, mg IV once daily is apckage in combination with a loop diuretic. In addition, diuretics may cause fluid and electrolyte imbalances and may precipitate or exacerbate urinary incontinence.

pqckage An increased risk of falls has been reported for elderly patients receiving thiazide diuretics. Sodium picosulfate; Magnesium oxide; Anhydrous citric acid: Avoid simultaneous administration with whole blood or its derivatives. Finally, both thiazides and sulfonylureas have been reported to cause photosensitivity reactions; concomitant use may increase the risk of photosensitivity. The first dose response acute postural hypotension of prazosin may be exaggerated in patients who are receiving beta-adrenergic blockers, diuretics, or other antihypertensive agents.


Chlorothiazide absorption from the GI tract is saturable.

Akorn – Sodium DiurilĀ® (chlorothiazide sodium)

Serum and urine electrolyte determinations are particularly important when the diurl is vomiting excessively or receiving parenteral fluids. Assess the patient’s potassium and magnesium concentration before and periodically during pasireotide receipt. Discontinuation of sertraline should be considered in patients who develop symptomatic hyponatremia. Atropine; Hyoscyamine; Phenobarbital; Scopolamine: Warning signs or symptoms of fluid and electrolyte imbalance, irrespective of cause, include dryness of mouth, thirst, weakness, lethargy, drowsiness, restlessness, confusion, seizures, muscle pains or cramps, muscular fatigue, hypotension, oliguria, tachycardia, and gastrointestinal disturbances such as nausea and vomiting.

Patients using cardiovascular drugs concomitantly with apraclonidine should have their pulse and blood pressure monitored periodically. Careful monitoring of blood pressure and hypotensive symptoms is recommended especially in patients with ischemic heart disease and in patients on antihypertensive agents.